Ultrasound department of Kharkiv Regional Perinatal Center. Kharkiv Medical Academy of postgraduated education, Ukraine.

Case report

Following images and video shows two cases of trisomy 13. The first one was a patient who presented for the exam very late during her pregnancy, at 37 weeks; the second one was diagnosed at 13 weeks of pregnancy. Subsequent karyotyping confirmed the diagnoses.

Case 1

Images 1, 2: 37 weeks of pregnancy, trisomy 13; the image 1 shows fetal head with macrocrania and alobar holoprosencephaly. The image 2 shows abnormal facial profile with absent nasal bones.

Images 3, 4: 37 weeks of pregnancy, trisomy 13; the images show postaxial polydactyly of the feet.

Video 1: 37 weeks of pregnancy, trisomy 13; the video shows abnormal fetal face with prominent forehead, depressed nasal bridge and hypotelorism.

Case 2

Images 5, 6: 13 weeks of gestation, trisomy 13; the image 5 shows oblique transverse scan of the fetal head with holoprosencephaly. The image 6 shows coronal scan of the fetal face with hypotelorism.

Images 7, 8: 13 weeks of gestation, trisomy 13; the image 7 shows hyperechoic bowels of the fetus. The image 8 shows color Doppler transverse scan of the fetal thorax at the level of the four chamber view of the heart with ventricular septal defect.

Image 9: 13 weeks of gestation, trisomy 13; the image shows omphalocele of the fetus.